Nashville native Isabelle Harrison played at Tennessee, where she was twice named first-team All-SEC, before the Phoenix Mercury selected her 12th overall in the 2015 WNBA draft. After stints with San Antonio/Las Vegas, Dallas, Chicago and New York, the veteran forward signed with the expansion Toronto Tempo in 2026. Harrison signed with Jordan Brand in 2022, her first shoe deal, and has worn the Jordan 40 in Wolf Grey, SL Metallic Copper and Bordeaux colorways.